M.E.S. Asmabi College, a premier educational institution managed by the Muslim Educational Society (Regd.) Calicut, owes its existence to the remarkable foresight and unremitting zeal of the late Dr. P.K. Abdul Gafoor, the late P.K. Abdulla I.A.S., Dr. M.A. Abdulla and late Dr. A.K. Siddiq Karikulam Azhikode.The institution was established in the year 1968 at P.Vemballur, Kodungallur, a remote coastal backward village in the S.N. Puram Panchayath, of Thrissur District. The main objective of the institution is to uplift the educationally backward community, especially Muslims of the area who had been denied of the right to education for generations.

The college now caters to the needs of the students throughout Kerala and Lakshadweep, cutting across the barriers of class, caste, creed and religion.Hajee Ismail Essa Sait of Cochin initially donated the land and building and the college was named after his mother "Asmabi".

The college which enjoys 2F and 12B status of the U.G.C. is affiliated to the Calicut University. At present it provides higher education to 2500 above students in seventeen Under Graduate Programmes, six Post Graduate Programmes and three Research centres. The College is re-accredited by the NAAC at B++ level in March 2019.